OFF-TARGET EFFECTS IN CRISPR/CAS9 GENE EDITING

Off-target effects in CRISPR/Cas9 gene editing

Gene editing stands for the methods to precisely make changes to a specific nucleic acid sequence.With the recent development of the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system, gene editing has become efficient, convenient and programmable, leading to promising translational studies and clinical trials for both g

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Extracellular vesicles in the Chronic Myeloid Leukemia scenario: an update about the shuttling of disease markers and therapeutic molecules

Extracellular vesicles (EVs) are various sets of cell-derived membranous structures containing lipids, nucleic acids, and proteins secreted by both eukaryotic and prokaryotic cells.It is now well recognized that EVs are Neff D94BHM1N0B 90cm Black Stainless Steel Chimney Hood key intercellular communication mediators, allowing the functional transfe

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Tourism and territorial structure in Ciudad Juarez, Mexico

This paper deals with the issue of the territorial structure of tourism in Ciudad Juarez, Mexico.To do this, the study is divided SHEA BUTTER CONDITIONER into two major parts: first, theoretical aspects, given support to our analysis, and a brief history of tourism in the Northern borderlands of Mexico are presented.Then, four basic components of t

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